The Ballad of Moe-Joe: A Wild West Adventure is a sequel to The Ballad of Little Joe, Moe and the Big Exit, Horse Play, Timon on the Range, Animal Barn, Jungle Slickers, Pest of the West, Over a Barrel, Apple Family Reunion and a parody of The Lone Ranger
A long time ago in a town named Tampa-Galloping-Gulch there lived a group of cow brothers and sisters is in the "Okie-Dokie Corral" when a 17-years-old Sheriff named Moe-Joe who lived in a wild west but one day on trainy the train lived a cowgirl earth pony named Applejack who read an apple tree a bedtime story but then a train-car door opened and met the two cow-button brothers of Tampa-Galloping-Gulch named Poll-Buck-Nuggets (poll's great-grandson) and his biggesr wild western sidekick Fred-Williams (fred's great-grandson) these two cowboys had come to her.
But when they arrived at the city called Appleloosa of Tampa-Galloping-Gulch Applejack's cousin Braeburn gives them the grand tour, explaining that the town was built in less than a year. The town includes a saloon called the Salt Block, a clock tower, a stage for musical performances, and acres of apple orchard, and has some of what Braeburn calls the "finest comforts" such as horse-drawn carriages, horse-drawn horse-drawn carriages, wild west dances, and mild west dances. The town is governed by Sheriff Silverstar. when Poll-Buck-Nuggets and Fred-Williams goes to a theater/saloon named Tampa-Kantina.
When Joe foretells a time when his brothers will bow down before him, their jealousy turns to spite, and they decide to sell him into slavery to The Scallions.
Moe-Joe got to be a Sheriff by Sweetie Drops and Shoeshine. But then a villain there boss Dead Eye Seney and his Dead Eye minions/brothers arrived there and He ends up working at a saloon for him and his unique skills quickly make him an invaluable employee. Also working at the saloon when he is named Employee of the Month in his place.
- The role of Little Joe's brother Izzy is played by Fifi Pea, sister to Jean-Claude and Phillipe.
- The real names of Joseph's brothers: Reuben, Simeon, Levi, Issachar, Zebulun, Gad, Asher, Dan, Naphtali, Judah, and Benjamin.
- There are two Beatles references surrounding Little Joe’s brother Jude when people greet him saying, “Hey, Jude!”
- There are some ads in Tampa-Galloping-Gulch from previous shows:
- Sweet Apple Acres (from Friendship is Magic, part 1, Applebuck Season, Griffon the Brush Off, Dragonshy, Winter Wrap Up, Call of the Cutie, Fall Weather Friends, Suited For Success, The Show Stoppers, Green Isn't Your Color, The Cutie Mark Chronicles, Party of One, The Return of Harmony Part 1 and 2, Lesson Zero, Sisterhooves Social, The Cutie Pox, Secret of My Excess, Family Appreciation Day, Baby Cakes, The Last Roundup, The Super Speedy Cider Squeezy 6000, Hearts and Hooves Day, A Friend in Deed, Ponyville Confidential, Too Many Pinkie Pies, One Bad Apple, Sleepless in Ponyville, Apple Family Reunion, Spike at Your Service, Keep Calm and Flutter On, Magical Mystery Cure, Princess Twilight Sparkle - Part 1, Castle Mane-ia, Bats!, Pinkie Apple Pie, Simple Ways, Filli Vanilli, Somepony to Watch Over Me, Maud Pie and Leap of Faith)
- Appleloosa (Over a Barrel, Pinkie Pride, Twilight's Kingdom - Part 1 and 2)
- Dodge Junction (from The Last Roundup)
- Dodge Junction train station (from The Last Roundup)
- Dodge Junction outhouse (from The Last Roundup)
- Cherry Hill Ranch orchards (from The Last Roundup)
- Cherry Hill Ranch, exterior view (from The Last Roundup)
- Rootin' Tootin' Pizza Place (from The Ballad of Little Joe and Moe and the Big Exit)
- Dodgeball City (from The Ballad of Little Joe and Moe and the Big Exit)
- "Okie-Dokie Corral" (from The Ballad of Little Joe)